A bottle of opened wine stored in the refrigerator lasts about 6 to 16 times longer than it would if stored at room temp. Keeping wine in the fridge slows down oxidation. The more wine in the bottle, the longer it will last because there’ll be less empty space and, therefore, potential oxygen. If you have less than half a bottle of wine left, it’s a good idea to decant it to a smaller bottle before refrigerating.